Original Research Open access Published: 22 Feb 2026

Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment

Eisha Nisar, Rong Chen, Atul Janardhan Butte

¹ Faisalabad Medical University, Faisalabad, Pakistan.
² Lucile Packard Children’s Hospital, Palo Alto, California, USA.

Journal of Experimental & Integrative Medicine volume 14 pages 1-5 (2026)

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Received 10 Oct 2025 Revised 9 Jan 2025 Accepted 18 Jan 2025 Published 22 Feb 2026 License CC BY 4.0

Keywords: Whole Genome Sequencing; Polygenic Risk Prediction; Artificial Intelligence; Machine Learning; Complex Disease Risk; Precision Medicine.

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Nisar, E., Chen, R. & Butte, A. J. Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment. J. Exp. Integr. Med. 14, 1–5 (2026). https://www.jeim.org/articles/2614101

Nisar, E., Chen, R., & Butte, A. J. (2026). Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment. Journal of Experimental & Integrative Medicine, 14(1), 1–5. https://www.jeim.org/articles/2614101

Eisha Nisar, et al.. "Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment." Journal of Experimental & Integrative Medicine, vol. 14, no. 1, 2026, pp. 1–5, https://www.jeim.org/articles/2614101.

Eisha Nisar, Rong Chen, Atul Janardhan Butte. "Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment." Journal of Experimental & Integrative Medicine 14, no. 1 (2026): 1–5. https://www.jeim.org/articles/2614101.

Nisar E, Chen R, Butte AJ. Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment. J. Exp. Integr. Med.. 2026;14(1):1-5. Available from: https://www.jeim.org/articles/2614101

@article{isar2026artificialintelligence,
  title = {Artificial Intelligence Driven Polygenic Risk Prediction Using Whole Genome Sequencing for Complex Disease Assessment},
  author = {Nisar, Eisha and Chen, Rong and Butte, Atul Janardhan},
  journal = {Journal of Experimental & Integrative Medicine},
  year = {2026},
  volume = {14},
  number = {1},
  pages = {1--5},
  url = {https://www.jeim.org/articles/2614101},
}